Non-steroidal anti-inflammatory drugs: What is the actual risk of liver damage?

What Is The “Safest” Non-Steroidal Anti-Inflammatory Drugs?

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) which are widely used in clinical practice are also very well-known for their various adverse reactions. Each NSAID has its own unique safety profile and selecting an appropriate NSAID must be individualized for each patient based on his or her medical needs and risk factors. We reviewed literatures on NSAIDs, focusing on their adverse reaction pro...

Non-steroidal anti-inflammatory drugs.

Non-steroidal anti-inflammatory drugs and the risk of psychosis.

The objective of the current research was to examine the relation between non-steroidal anti-inflammatory drugs (NSAID) use and risk of psychosis. To this end we performed a longitudinal case-control study using prescription data from a Dutch health insurance company. Men aged 25 years or over and women aged 30 years or over were excluded to prevent inclusion of non-incident cases. This resulte...

Hepatocellular damage from non-steroidal anti-inflammatory drugs.

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for the management of rheumatological disorders, and as analgesics and antipyretics. Hepatotoxicity is an uncommon, but potentially lethal complication, which usually occurs within 12 weeks of starting therapy. It can occur with all NSAIDs, but appears to be more common with diclofenac and particularly sulindac. Female patients aged...

Non-steroidal anti-inflammatory drugs: is the balance shifting?

Non-steroidal anti-inflammatory drugs (NSAIDs) have been subject to repeated warnings about their adverse drug reaction profile. The emphasis is usually on upper gastrointestinal tract complications [1-3] but, with concern about the lower gut [4, 5] and other organ systems [6], a view has been advanced that NSAIDs can be bad for patients and that the prescription rate should be reduced [7]. hi ...